In a skillet over medium heat, cook the ground beef and onion until the beef is browned and the onion is soft. Drain any grease.
Stir in the red enchilada sauce, green chiles, black beans, and corn. Season with salt and pepper.
Lightly coat the inside of a slow cooker with non-stick spray.
Spread a layer of tortilla strips on the bottom.
Top with a portion of the beef mixture, then sprinkle with cheese.
Repeat the layers until all ingredients are used, ending with cheese on top.
Cover and cook on low for 4–5 hours or on high for 2–3 hours, until heated through and the cheese is melted.