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–+ servings

Slow Cooker Dr. Pepper Meatloaf

This Slow Cooker Dr. Pepper Meatloaf is a tender, flavorful family favorite topped with a sweet and smoky glaze that makes weeknight dinners effortless and comforting.
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A plate with two slices of meatloaf on mashed potatoes sits on a red checkered cloth, with a can of Dr Pepper and a glass of iced drink in the background.
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Prep Time:5 minutes
Cook Time:6 hours
Total Time:6 hours 5 minutes

Ingredients

  • ¾ cup milk
  • ⅔ cup seasoned bread crumbs
  • 2 eggs
  • 2 teaspoons dried minced onion
  • 1 clove garlic minced
  • 1 tablespoon mustard
  • 1 tablespoon bbq sauce
  • 1 tablespoon Worcestershire sauce
  • ¼ teaspoon seasoning salt
  • ¼ teaspoon black pepper
  • 2 pounds lean ground beef

Glaze

  • ½ cup Dr. Pepper
  • ½ cup BBQ Sauce
  • 2 tablespoons brown sugar

Instructions

  • Step 1: Prepare the breadcrumb mixture - In a large mixing bowl, combine the milk and seasoned bread crumbs. Stir until the crumbs are fully moistened and soft. This step is important because it keeps the meatloaf tender instead of dense.
  • Step 2: Add the flavor builders - Crack the eggs into the bowl, then add the dried minced onion, minced garlic, mustard, BBQ sauce, Worcestershire sauce, seasoning salt, and black pepper. Stir everything together until well combined.
  • Step 3: Mix in the ground beef - Add the lean ground beef to the bowl. Using a wooden spoon or clean hands, gently mix until everything is evenly incorporated. Be careful not to overmix, as that can make the meatloaf tough.
  • Step 4: Shape the meatloaf - Line your slow cooker with foil, leaving enough overhang to lift the meatloaf out later. Shape the meat mixture into an oval loaf and place it gently into the bottom of the slow cooker.
  • Step 5: Make the glaze - In a small bowl, combine the Dr. Pepper, BBQ sauce, and brown sugar. Stir until the sugar is mostly dissolved and the glaze is smooth.
  • Step 6: Glaze and cook - Pour half of the glaze over the meatloaf, spreading it evenly across the top. Cover the slow cooker and cook on low for 6 hours or on high for 4 hours, until the meatloaf is cooked through.
  • Step 7: Optional broil for extra flavor - If you want a sticky, caramelized finish, carefully lift the meatloaf out using the foil and transfer it to a baking sheet. Spoon the remaining glaze over the top and broil for 2 to 3 minutes, keeping a close eye on it.
  • Step 8: Slice and serve - Let the meatloaf rest for a few minutes before slicing. Serve warm and enjoy every comforting bite.

Notes

Tips, Tricks & Storage

Here are a few tips and tricks I’ve picked up while tinkering around with this recipe.
Cook on Low
If you have time, cooking on low allows the flavors to blend gradually and keeps the meatloaf from drying out. If it cooks too long, just drizzle a little extra Dr. Pepper or broth over it before serving to restore moisture.
Line the Slow Cooker with Foil
Lining your slow cooker with foil (and leaving a bit of overhang) makes it easy to lift the loaf out when it's done and helps minimize cleanup from caramelized bits.
Let It Rest Before Slicing
Once cooked, let the meatloaf rest for 10–15 minutes before slicing. This short wait allows the juices to settle, so each slice stays firm and flavorful.
Storage
Store leftover slices in an airtight container in the fridge for up to 3 days. Reheat gently in the oven, skillet, or air fryer for the best texture. You can also freeze individual portions for up to 2 months and just thaw overnight before reheating.

Variations

Want to sneak in extra veggies? Stir in finely chopped bell peppers, carrots, or mushrooms for a boost of flavor and texture. If you like a bit of heat, add diced jalapeños, a dash of cayenne, or a swirl of your favorite hot sauce right into the mix. You can even switch up the glaze—try blending Dr. Pepper with ketchup, BBQ sauce, or a splash of soy sauce for something richer and more complex. Hosting a group? Shape the mixture into mini loaves or muffin-sized portions for quicker, party-ready servings. However you tweak it, this meatloaf is forgiving and welcomes your own twist while keeping that same comfort food feel.

Substitutions

Missing something or just trying to use what’s already in the fridge or pantry? This recipe is flexible. Use what you have around the house!
Ground Beef → Ground Turkey or Chicken
While of course it changes the flavor palate, swap in leaner meat like Turkey or Chicken for a lighter take. The Dr. Pepper keeps it juicy with any meat that you use.
Breadcrumbs → Oats or Crushed Crackers
If you're out of breadcrumbs, quick oats, or crushed crackers bind the loaf just as well and soak up moisture beautifully.
Dr. Pepper → Cola or Root Beer
Any dark soda works here. Cola gives a classic sweetness, while root beer adds a hint of spice.
Ketchup or BBQ Sauce → Tomato Sauce + Honey or Molasses
If you're short on glaze ingredients, combine tomato sauce with a touch of honey, molasses, or brown sugar for a homemade replacement.
Onion → Shallot or Green Onion
If you're low on regular onions, use shallots for sweetness or green onions for a mild flavor.

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Servings: 4 people
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